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Walter Williams (Brian Donlevy) is a take-charge captain of industry who has worked his way up in a San Francisco steel company from a position as a sheet metal worker. He loves his wife Irene (Helen Walker) very much and they have planned a vacation drive together. Irene cancels at the last minute claiming a toothache, but asks that Walter drive her cousin Jim Torrance (Tony B...。在一个冬夜，小偷陈文才偷了辆出租车。他原本打算用来敲诈勒索，计划却被一名路人意外打断。这群人拿出丰厚的酬金，陈受不住诱惑决定载他们一程。然而陈不知道，其中一个男人已经感染了未知病毒。当车辆被警方拦下，车内的行车记录仪和警察的执法记录仪不仅拍下了病毒传播的瞬间，还揭示了所有乘客的悲惨命运。随着混乱迅速蔓延全城，人类的命运岌岌可危。。